Forschungsthemen des AK Mazik

 

Supramolekulare Motive im kristallinen Zustand

Wasserstoffbrückenmuster und Wassercluster

Wassercluster

R. Rosin, W. Seichter, A. Schwarzer, M. Mazik, Eur. J. Org. Chem. 2017, 6038-6051.
„1,8-Naphthyridine carbaldehydes and their methyl-substituted precursors: Synthesis, molecular structures, supramolecular motifs and trapped water clusters“

 

Halogenbrücken

Halogenbrückenmuster

P. Seidel, A. Schwarzer, M. Mazik, Eur. J. Org. Chem. 2019, 1493-1502.
„Fluorene Derivatives Bearing Halogenomethyl Groups: Synthesis, Molecular Structures, and Halogen/Hydrogen Bonding Patterns in the Crystalline State”

 

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Entwicklung von künstlichen Kohlenhydratrezeptoren


Kohlenhydratrezeptoren

F. Amrhein, J. Lippe, M. Mazik, Org. Biomol. Chem. 2016, 14, 10648-10659.
„Carbohydrate receptors combining both a macrocyclic building block and flexible side arms as recognition units: Binding properties of compounds with CH2OH groups as side arms“

 

weitere Beispiele


Kohlenhydratrezeptoren

J. Lippe, M. Mazik, J. Org. Chem. 2015, 80, 1427-1439.
„Carbohydrate receptors combining both a macrocyclic building block and flexible side-arms as recognition units: design, syntheses and binding studies"

 

 

Kohlenhydratrezeptoren

J. Lippe, W. Seichter, M. Mazik, Org. Biomol. Chem. 2015, 13, 11622-11632.
“Improved binding affinity and interesting selectivities of aminopyrimidine-bearing carbohydrate receptors in comparison with their aminopyridine analogues”

 

 

Kohlenhydratrezeptoren

J.-R. Rosien, W. Seichter, M. Mazik, Org. Biomol. Chem. 2013, 11, 6569-6579.>br> „Trimethoxybenzene- and trimethylbenzene-based compounds bearing imidazole, indole and pyrrole groups as recognition units: synthesis and evaluation of the binding properties towards carbohydrates"

 

 

Kohlenhydratrezeptoren

N. Koch, W. Seichter, M. Mazik, Synthesis 2016, 48, 2757-2767.
„Compounds based on a triethyl- or trimethoxybenzene scaffold bearing pyrazole, pyridine, and pyrimidine groups: Syntheses and representative binding studies towards carbohydrates“

 

 

Kohlenhydratrezeptoren

N. Koch, J.-R. Rosien, M. Mazik, Tetrahedron 2014, 70, 8758-8767.
„Synthesis of compounds based on a dimesitylmethane scaffold and representative binding studies showing di- vs. monosaccharide preference”

 

 

Kohlenhydratrezeptoren

C. Geffert, M. Kuschel, M. Mazik, J. Org. Chem. 2013, 78, 292-300.
„Molecular Recognition of N-Acetylneuraminic Acid by Acyclic Pyridinium- and Quinolinium-Based Receptors in Aqueous Media: Recognition through Combination of Cationic and Neutral Recognition Sites"

 

 

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Ionenpaarerkennung mit artifiziellen Systemen 

Ionenpaarerkennung

M. Stapf, W. Seichter, M. Mazik, Chem. Eur. J. 2015, 21, 6350-6354.
“Unique hydrogen-bonded complex of hydronium and hydroxide ions”

 

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Entwicklung von Systemen für Anwendungen in der chemischen Sensorik

Entwicklung von Sensoren für Ammoniumionen

Erkennung von Ammoniumionen

M. Schulze, N. Koch, W. Seichter, M. Mazik, Eur. J. Org. Chem. 2018, 4317-4330.
„Crystalline ammonium complexes of trimethyl- and triethylbenzene-based tripodal compounds bearing pyrazole and indazole groups“

 

weitere Beispiele


Erkennung von Ammoniumionen

N. Koch, W. Seichter, M. Mazik, Tetrahedron 2015, 71, 8965-8974.
“Hexapodal pyrazole-based receptors: Complexes with ammonium ions and solvent molecules in the solid state”

 

 

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Selektive Liganden für strategische Elemente

Selektive Extraktion von Indiumionen aus sauren wässrigen Lösungen

Indiumextraktion

M. M. Schulze, R. Löwe, R. Pollex, M. Mazik, Monatsh. Chem. 2019, 150, 983-990.
“Structure–extractability relationships for substituted 8-hydroxyquinolines: solvent extraction of indium ions from acidic aqueous media”

 

weitere Beispiele

Kristalline Ligand-Indium(III)-Komplexe

Indiumkomplex

M. M. Schulze, A. Schwarzer, W. Seichter, M. Mazik, 2019
“Crystal structure of [In4(apoH)23-OH)2Cl10(μ-Cl)]3- 3 HNEt3+ THF solvate”

 

 

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Konformationsanalyse

Konformationsanalyse

M. Schulze, A. Schwarzer, M. Mazik, CrystEngComm 2017, 19, 4003-4016.
„Conformations of benzene-based tripodal isatin-bearing compounds in the crystalline state“

 

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